Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10970621 | 0.92 | HSP90AB1 (0.44) | KDM4EALDH1A1MAPTHSD17B10TSHR | |
| SCHEMBL22123487 | 0.85 | ALDH1A1 (0.42) | PARP1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL40536 | 0.83 | ALDH1A1 (0.54) | PARP1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL11651879 | 0.82 | KDM4E (0.47) | PARP1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL9632452 | 0.82 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL7833654 | 0.82 | ALDH1A1 (0.50) | PARP1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL9058909 | 0.81 | GABRA1 (0.43) | KDM4EALDH1A1LMNAHIF1ATDP1 | |
| SCHEMBL7547028 | 0.81 | CD44 (0.43) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL15958950 | 0.81 | G6PD (0.60) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL28756376 | 0.80 | KDM4E (0.46) | PARP1KDM4EALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830614-A | Multilayer organic photoreceptor employing a dual layer of charge transporting polymers | XEROX CORPORATION (US) | 1998-11-03 | — | — | US | claimed |