Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27741091 | 0.74 | CHRM2 (0.42) | BCHELMNAALDH1A1MAPK1MAOB | |
| SCHEMBL11175416 | 0.70 | MAPK1 (0.48) | BCHELMNAALDH1A1MAPK1CHRM2 | |
| SCHEMBL29117240 | 0.70 | CTSL (0.49) | BCHELMNAALDH1A1MAPK1MAOB | |
| SCHEMBL29117236 | 0.70 | CTSL (0.49) | BCHELMNAALDH1A1MAPK1MAOB | |
| SCHEMBL29117319 | 0.68 | PRMT5 (0.56) | GPR119 | |
| SCHEMBL12607070 | 0.68 | PRMT5 (0.56) | GPR119 | |
| SCHEMBL12607067 | 0.68 | PRMT5 (0.56) | GPR119 | |
| SCHEMBL14047773 | 0.68 | CHRM2 (0.71) | LMNAALDH1A1MAPK1CHRM2CHRM1 | |
| SCHEMBL27741092 | 0.68 | DRD2 (0.50) | BCHELMNAALDH1A1MAPK1MAOB | |
| SCHEMBL2977297 | 0.67 | MEN1 (0.55) | BCHEALDH1A1KMT2AGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750536-A | ANTI-ASTHMATICS, TREATMENT OF PAIN SENSITIVITY | DOMPE ' SPA (IT) | 1998-05-12 | — | — | US | disclosed |