Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 4/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789433 | 0.76 | CHRNB2 (0.53) | ALDH1A1LMNAMAPK1BCHETMEM97 | |
| SCHEMBL11175416 | 0.75 | MAPK1 (0.48) | CHRM2CHRM1CHRM3ALDH1A1LMNA | |
| SCHEMBL29117236 | 0.75 | CTSL (0.49) | CHRM2CHRM1CHRM3AGTR2ALDH1A1 | |
| SCHEMBL29117240 | 0.75 | CTSL (0.49) | CHRM2CHRM1CHRM3AGTR2ALDH1A1 | |
| SCHEMBL27741092 | 0.74 | DRD2 (0.50) | CHRM2CHRM1CHRM3ALDH1A1LMNA | |
| SCHEMBL18615751 | 0.74 | HRH3 (0.51) | AGTR2TMEM97SIGMAR1CARM1PRMT6 | |
| SCHEMBL21779383 | 0.74 | HRH3 (0.51) | AGTR2TMEM97SIGMAR1CARM1PRMT6 | |
| SCHEMBL8691838 | 0.74 | BCHE (0.40) | CHRM2CHRM1CHRM3AGTR2ALDH1A1 | |
| SCHEMBL6099133 | 0.73 | CHRM2 (0.39) | CHRM2CHRM1CHRM3AGTR2ALDH1A1 | |
| SCHEMBL14047773 | 0.73 | CHRM2 (0.71) | CHRM2CHRM1CHRM3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101384602-A | Novel, cyclic substituted furopyrimidine derivatives and use thereof for treating cardiovascular diseases | BAYER HEALTHCARE AG (DE) | 2009-03-11 | — | — | CN | disclosed |