Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 2/20 | 0.49 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.41 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2287924 | 0.78 | FEN1 (0.43) | FEN1ALDH1A1TSHRCYP2C19PDE4A | |
| SCHEMBL18088031 | 0.78 | KCNA3 (0.46) | KCNA3TSHRKMT2ALMNASMN1; SMN2 | |
| SCHEMBL15432334 | 0.77 | FEN1 (0.53) | FEN1ALDH1A1CYP2C19PDE4APDE4B | |
| SCHEMBL13402676 | 0.77 | FEN1 (0.56) | FEN1ALDH1A1CYP2C19PDE4DEGFR | |
| SCHEMBL18074146 | 0.76 | KCNA3 (0.44) | KCNA3ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL13787017 | 0.75 | CYP11B2 (0.51) | FEN1ALDH1A1TSHRCYP2C19EGFR | |
| SCHEMBL13377295 | 0.73 | FEN1 (0.49) | FEN1ALDH1A1CYP2C19PDE4APDE4B | |
| SCHEMBL8696587 | 0.72 | HSD17B10 (0.60) | FEN1KCNA3ALDH1A1TSHRCYP2C19 | |
| SCHEMBL18073980 | 0.71 | KCNA3 (0.46) | KCNA3ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6636299 | 0.71 | PADI4 (0.47) | FEN1ALDH1A1KMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817670-A | RESPIRATORY SYSTEM DISORDERS, ORGAN TRANSPLANTATION, ANTITUMOR AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| EP-0779292-A1 | NOVEL NAPHTHYRIDINE DERIVATIVE AND MEDICINAL COMPOSITION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-06-18 | — | — | EP | disclosed |