Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 9/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.37 |
| ▸ | GHSR | Q92847 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8691887 | 0.86 | GHSR (0.42) | SLC6A2SLC6A4SLC6A3GHSR | |
| Hydrochloric Acid SCHEMBL8693010 | 0.85 | GHSR (0.42) | SLC6A2SLC6A4SLC6A3GHSR | |
| Hydrochloric Acid SCHEMBL8691113 | 0.73 | SIGMAR1 (0.38) | SLC6A2SLC6A4SLC6A3GHSRL3MBTL1 | |
| SCHEMBL8694229 | 0.72 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3GHSRL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8693208 | 0.71 | SIGMAR1 (0.36) | SLC6A2SLC6A4SLC6A3GHSRSIGMAR1 | |
| SCHEMBL6182634 | 0.64 | SLC6A3 (0.46) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6182630 | 0.64 | SLC6A3 (0.46) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23356458 | 0.63 | CHRNA7 (0.44) | SLC6A2SLC6A4SLC6A3L3MBTL1SIGMAR1 | |
| SCHEMBL23356459 | 0.63 | CHRNA7 (0.44) | SLC6A2SLC6A4SLC6A3L3MBTL1SIGMAR1 | |
| SCHEMBL2299159 | 0.63 | SLC6A4 (0.54) | SLC6A2SLC6A4SLC6A3L3MBTL1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760035-A | PIPERIDINE COMPOUNDS SUBSTITUTED WITH AN AMINOALKYL GROUP AND AN ARYLOXYALKYL GROUP, ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, IMMUNOSUPPRESSANTS | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-06-02 | — | — | US | disclosed |