Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8691635 | 0.85 | MAPK1 (0.33) | KDM4EKMT2APTGS1PTGS2 | |
| SCHEMBL8689597 | 0.81 | RAB9A (0.38) | KDM4EKMT2APTGS1PTGS2 | |
| SCHEMBL8635861 | 0.80 | ALDH1A1 (0.37) | KDM4EKMT2APTGS1PTGS2 | |
| SCHEMBL6343151 | 0.74 | PTGS2 (0.48) | PTGS1PTGS2 | |
| SCHEMBL8689450 | 0.73 | ALDH1A1 (0.46) | — | |
| SCHEMBL8688860 | 0.68 | PTGS2 (0.52) | PTGS1PTGS2 | |
| SCHEMBL8635921 | 0.68 | PTGS2 (0.46) | PTGS1PTGS2 | |
| SCHEMBL7112165 | 0.66 | PTGS2 (0.51) | KDM4EKMT2APTGS1PTGS2 | |
| SCHEMBL8692224 | 0.66 | PTGS2 (0.38) | KDM4EPTGS1PTGS2 | |
| SCHEMBL8693447 | 0.66 | PTGS2 (0.38) | KMT2APTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760068-A | NONSTEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G.D. SEARLE & CO. (US) | 1998-06-02 | — | — | US | disclosed |
| US-5756529-A | ANTIINFLAMMATORY | G.D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |