Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.30 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.30 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.30 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26092373 | 0.77 | BLM (0.31) | SMN1; SMN2HIF1A | |
| SCHEMBL19031974 | 0.76 | ALOX5AP (0.41) | GPR119MAPK1NPSR1KDM4CKDM4E | |
| SCHEMBL21602032 | 0.75 | PKM (0.37) | SCN9AGPR119MAPK1NPSR1KDM4C | |
| SCHEMBL3901063 | 0.75 | SLC6A3 (0.37) | GPR119MAPK1NPSR1KDM4CKDM4E | |
| SCHEMBL27476791 | 0.74 | CTSS (0.46) | KDM4CKDM4ESMN1; SMN2HIF1ACTSK | |
| SCHEMBL27997582 | 0.74 | MAPK1 (0.36) | GPR119MAPK1NPSR1KDM4CKDM4E | |
| SCHEMBL27763466 | 0.72 | MAPK1 (0.39) | GPR119MAPK1NPSR1KDM4CKDM4E | |
| SCHEMBL5459873 | 0.72 | ALDH1A1 (0.36) | PKMSMN1; SMN2HIF1AALOX5ALOX5AP | |
| SCHEMBL27629811 | 0.72 | ALDH1A1 (0.36) | PKMSMN1; SMN2HIF1AALOX5ALOX5AP | |
| SCHEMBL28800028 | 0.72 | MEN1 (0.36) | NPSR1SMN1; SMN2HIF1ACTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756832-A | REACTING AN ALDHYDE WITH AN ORTHOFORMATE IN THE PRESENCE OF AN ACID CATALYST AND AN ALCOHOL | BRISTOL-MYERS SQUIBB CO. (US) | 1998-05-26 | — | — | US | disclosed |
| US-5672599-A | DUAL ACTION ANGIOTENSIN CONVERTING ENZYME INHIBITORS AND NEUTRAL ENDOPEPTIDASE INHIBITORS; TREATMENT OF CARDIOVASCULAR DISORDERS | BRISTOL-MYERS SQUIBB CO. (US) | 1997-09-30 | — | — | US | disclosed |
| US-5670699-A | Process for preparing amino acid esters useful as intermediates for compounds containing a fused bicyclic ring | BRISTOL-MYERS SQUIBB CO. (US) | 1997-09-23 | — | — | US | disclosed |