Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 8/20 | 0.50 |
| ▸ | RARA | P10276 | 5/20 | 0.50 |
| ▸ | RARB | P10826 | 5/20 | 0.50 |
| ▸ | RXRA | P19793 | 5/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8688418 | 0.93 | RARA (0.47) | RARGRARARARBRXRAPLA2G2A | |
| SCHEMBL8656079 | 0.89 | RARG (0.58) | RARGRARARARBRXRARXRB | |
| SCHEMBL8688231 | 0.87 | RARG (0.55) | RARGRARARARBRXRACYP3A4 | |
| SCHEMBL8442921 | 0.81 | RARG (0.55) | RARGRARARARBRXRA | |
| SCHEMBL8660116 | 0.81 | RARB (0.56) | RARGRARARARBRXRACYP3A4 | |
| SCHEMBL8690673 | 0.80 | RARG (0.55) | RARGRARARARBRXRACYP3A4 | |
| SCHEMBL6379832 | 0.76 | RARG (0.64) | RARGRARARARBRXRACYP26A1 | |
| SCHEMBL8438448 | 0.76 | PTPN11 (0.61) | RARGRARARARBRXRA | |
| SCHEMBL28519834 | 0.75 | TDP1 (0.51) | PLA2G2A | |
| SCHEMBL17327789 | 0.74 | RARB (0.56) | RARGRARARARBRXRACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723499-A | Polycyclic aromatic compounds and pharmaceutical/cosmetic compositions comprised thereof | C.I.R.D. GALDERMA (FR) | 1998-03-03 | — | — | US | disclosed |