Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 4/20 | 0.53 |
| ▸ | PPARA | Q07869 | 4/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGAV | P06756 | 1/20 | 0.48 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.48 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MDH2 | P40926 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019368 | 0.91 | FFAR1 (0.53) | PPARDPPARAPPARGFFAR1TNKS2 | |
| SCHEMBL8695194 | 0.91 | PPARD (0.58) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL8695196 | 0.81 | FFAR1 (0.64) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL3882956 | 0.79 | MAOB (0.56) | FFAR1PARP10FFAR4SPHK2SPHK1 | |
| SCHEMBL8905373 | 0.75 | CYP2A6 (0.58) | SMN1; SMN2 | |
| SCHEMBL30138881 | 0.75 | CYP2A6 (0.58) | SMN1; SMN2 | |
| SCHEMBL7405256 | 0.75 | PPARD (0.48) | PPARDPPARAPPARGFFAR1TNKS2 | |
| SCHEMBL5441264 | 0.74 | MAOB (0.51) | PPARDPPARAPPARGTNKS2PARP2 | |
| SCHEMBL2912575 | 0.74 | FFAR1 (0.66) | FFAR1PARP10FFAR4SMN1; SMN2SPHK2 | |
| SCHEMBL2170636 | 0.74 | FFAR1 (0.77) | FFAR1PARP10FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721276-A | TREATING DISORDERS OF MELATONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1998-02-24 | — | — | US | disclosed |