Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9343594 | 0.82 | ALDH1A1 (0.45) | KMT2AALDH1A1LMNAMAPTPOLB | |
| SCHEMBL7887352 | 0.80 | GSK3A (0.43) | GSK3AGSK3BKMT2AALDH1A1MAPT | |
| SCHEMBL7888772 | 0.80 | GSK3A (0.40) | GSK3AGSK3BKMT2AALDH1A1LMNA | |
| SCHEMBL8700806 | 0.80 | GSK3A (0.37) | GSK3AGSK3BKMT2AALDH1A1PTGS1 | |
| SCHEMBL8993528 | 0.80 | SMN1; SMN2 (0.44) | GSK3AGSK3BKMT2AALDH1A1LMNA | |
| SCHEMBL7846203 | 0.80 | GSK3A (0.37) | GSK3AGSK3BKMT2AALDH1A1HTT | |
| SCHEMBL6920290 | 0.78 | VCAM1 (0.41) | SIRT6KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL7557543 | 0.78 | GSK3A (0.46) | GSK3AGSK3BALDH1A1PTGS1LMNA | |
| SCHEMBL7047509 | 0.76 | NPC1 (0.42) | KMT2AALDH1A1LMNASMN1; SMN2NPC1 | |
| SCHEMBL3243992 | 0.74 | ALDH1A1 (0.38) | SIRT6KMT2AALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018768-A1 | HERBICIDAL 3-(BICYCLIC NITROGEN-CONTAINING HETEROCYCLE)-SUBSTITUTED-1-METHYL-6-TRIFLUOROMETHYLURACILS | FMC CORPORATION (US) | 1998-05-07 | — | — | WO | disclosed |
| US-5661108-A | CONTROLLING PLANT GROWTH | FMC CORPORATION (US) | 1997-08-26 | — | — | US | disclosed |