Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.51 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.51 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.51 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636822 | 0.92 | PPARG (0.55) | ALDH1A1CYP2C9POLBPTGS2PTGS1 | |
| SCHEMBL8688557 | 0.91 | PTGS2 (0.52) | ALDH1A1CYP2C9POLBPTGS2PTGS1 | |
| SCHEMBL8693708 | 0.88 | POLB (0.67) | ALDH1A1CYP2C9POLBPTGS2PTGS1 | |
| SCHEMBL8691662 | 0.80 | ALDH1A1 (0.57) | ALDH1A1CYP2C9POLBPTGS2PTGS1 | |
| SCHEMBL25351301 | 0.79 | ALDH1A1 (0.60) | ALDH1A1CYP2C9POLBGLAKMT2A | |
| SCHEMBL1780615 | 0.78 | KCNJ6 (0.67) | ALDH1A1PTGS1KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL2834738 | 0.78 | ALDH1A1 (0.59) | ALDH1A1CYP2C9POLBGLACYP2C19 | |
| SCHEMBL8953991 | 0.77 | ALDH1A1 (0.57) | ALDH1A1CYP2C9POLBGLACYP2C19 | |
| SCHEMBL2837826 | 0.77 | ALDH1A1 (0.57) | ALDH1A1CYP2C9POLBPTGS2GLA | |
| SCHEMBL19258547 | 0.75 | KCNJ6 (0.63) | ALDH1A1PTGS1KCNJ6KCNJ5KCNJ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760068-A | NONSTEROIDAL ANTIINFLAMMATORY AGENTS WITH REDUCED SIDE EFFECTS | G.D. SEARLE & CO. (US) | 1998-06-02 | — | — | US | disclosed |
| US-5756529-A | ANTIINFLAMMATORY | G.D. SEARLE & CO. (US) | 1998-05-26 | — | — | US | disclosed |