Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.45 |
| ▸ | TMPRSS6 | Q8IU80 | 4/20 | 0.45 |
| ▸ | MASP2 | O00187 | 1/20 | 0.45 |
| ▸ | TMPRSS11D | O60235 | 2/20 | 0.45 |
| ▸ | PROC | P04070 | 1/20 | 0.44 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5028604 | 0.84 | SIGMAR1 (0.53) | CAPN1ACE | |
| SCHEMBL24288430 | 0.84 | SIGMAR1 (0.53) | CAPN1ACE | |
| SCHEMBL27467679 | 0.80 | CAPN1 (0.42) | F2ITGB3ITGA2BCAPN1F7 | |
| SCHEMBL7170752 | 0.75 | CAPN1 (0.54) | CAPN1ACE | |
| SCHEMBL7170754 | 0.75 | CAPN1 (0.54) | CAPN1ACE | |
| SCHEMBL16372685 | 0.73 | ADH1B (0.47) | CAPN1ACE | |
| SCHEMBL18494852 | 0.73 | ACE (0.49) | CAPN1ACE | |
| SCHEMBL8245648 | 0.73 | ADH1B (0.47) | CAPN1ACE | |
| SCHEMBL7450129 | 0.71 | PRSS1 (0.50) | F2TMPRSS6MASP2ITGB3ITGA2B | |
| SCHEMBL7140360 | 0.71 | PRSS1 (0.50) | F2TMPRSS6MASP2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705487-A | PEPTIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1998-01-06 | — | — | US | claimed |