⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9060804 | 0.85 | LTB4R2 (0.44) | — | |
| SCHEMBL8690657 | 0.80 | HTT (0.44) | — | |
| SCHEMBL8693592 | 0.75 | HTT (0.42) | — | |
| SCHEMBL6606838 | 0.71 | AGTR1 (0.53) | — | |
| SCHEMBL9367027 | 0.69 | PPARG (0.52) | — | |
| SCHEMBL8553595 | 0.68 | LTB4R2 (0.45) | — | |
| SCHEMBL9042464 | 0.68 | AGTR1 (0.49) | — | |
| SCHEMBL8691735 | 0.68 | SMAD3 (0.40) | — | |
| SCHEMBL6606668 | 0.68 | KDM4E (0.55) | — | |
| SCHEMBL1892549 | 0.68 | MME (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827863-A | Pyrazole derivatives as angiotensin II antagonists | J. URIACH & CIA, S.A. (ES) | 1998-10-27 | — | — | US | disclosed |
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |
| WO-1996004273-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA, S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |