Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8694595 | 0.85 | — | — | |
| SCHEMBL8690657 | 0.81 | HTT (0.44) | — | |
| SCHEMBL8693592 | 0.75 | HTT (0.42) | — | |
| SCHEMBL8696753 | 0.74 | SLC6A3 (0.42) | LTB4R2 | |
| SCHEMBL9042464 | 0.71 | AGTR1 (0.49) | AGTR1 | |
| SCHEMBL9429975 | 0.69 | SMN1; SMN2 (0.55) | LTB4R2AGTR1 | |
| SCHEMBL9427527 | 0.69 | AGTR1 (0.49) | LTB4R2AGTR1PPARG | |
| SCHEMBL8691735 | 0.69 | SMAD3 (0.40) | — | |
| SCHEMBL29979869 | 0.68 | SLC6A3 (0.69) | LTB4R2AGTR1 | |
| SCHEMBL14326964 | 0.68 | SLC6A3 (0.69) | LTB4R2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |