Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 10/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698313 | 0.94 | CD274 (0.39) | CD274PDCD1MTNR1AFFAR4MPO | |
| SCHEMBL8702158 | 0.85 | MTNR1A (0.40) | MTNR1A | |
| SCHEMBL8696466 | 0.80 | CD274 (0.55) | CD274PDCD1MTNR1ATLR8FFAR4 | |
| SCHEMBL7382950 | 0.77 | PTGER1 (0.35) | MTNR1AATMMPOCYP2C19 | |
| SCHEMBL8702156 | 0.75 | NPC1 (0.42) | — | |
| SCHEMBL8702166 | 0.74 | LTB4R2 (0.42) | — | |
| SCHEMBL4436864 | 0.73 | MKNK1 (0.47) | CYP2C19 | |
| SCHEMBL8699097 | 0.73 | CD274 (0.57) | CD274PDCD1MTNR1AFFAR4EPHX1 | |
| SCHEMBL8701532 | 0.72 | ALDH1A1 (0.46) | ATM | |
| SCHEMBL8696572 | 0.72 | CD274 (0.46) | CD274PDCD1MTNR1ATLR8FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | claimed |
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |