Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | TACR1 | P25103 | 6/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696242 | 0.78 | ALDH1A1 (0.66) | ALDH1A1HPGDHSD17B10EGFRTACR1 | |
| SCHEMBL8701787 | 0.76 | HDAC10 (0.44) | MEN1KMT2AMAPT | |
| SCHEMBL8698313 | 0.75 | CD274 (0.39) | — | |
| SCHEMBL8695083 | 0.72 | CD274 (0.38) | ATM | |
| SCHEMBL8697966 | 0.71 | ALDH1A1 (0.53) | ALDH1A1HPGDHSD17B10EGFRTACR1 | |
| SCHEMBL7382950 | 0.71 | PTGER1 (0.35) | HSD17B10EGFRATM | |
| SCHEMBL8701536 | 0.70 | HDAC3 (0.51) | ALDH1A1HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL4436864 | 0.70 | MKNK1 (0.47) | ALDH1A1HPGDHSD17B10KDM4ENPC1 | |
| SCHEMBL9709552 | 0.69 | IAPP (0.40) | — | |
| SCHEMBL9709582 | 0.68 | IAPP (0.39) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | claimed |
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |