SCHEMBL869595

SCHEMBL869595

[CH2]c1ccc(CC=C(C)C(=O)O)cc1

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.37
TRPA1 O75762 1/20 0.37
CYP2C9 P11712 1/20 0.37
PPARG P37231 1/20 0.35
BACE1 P56817 1/20 0.34
TBXAS1 P24557 3/20 0.33
HDAC8 Q9BY41 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32
SLC22A12 Q96S37 5/20 0.32
HTT P42858 1/20 0.32
LMNA P02545 1/20 0.32
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1921014 0.83 CTBP2 (0.44) AKR1C3TRPA1CYP2C9PPARGLMNA
SCHEMBL4266765 0.83 MEN1 (0.42) AKR1C3CYP1A2SLC22A12LMNAKMT2A
SCHEMBL5421635 0.83 CA2 (0.45) AKR1C3TRPA1CYP2C9BACE1SLC22A12
SCHEMBL7634720 0.83 TRPA1 (0.42) AKR1C3TRPA1CYP2C9PPARGBACE1
SCHEMBL8615571 0.83 MEN1 (0.42) AKR1C3CYP1A2SLC22A12LMNAKMT2A
SCHEMBL1921017 0.83 CTBP2 (0.44) AKR1C3TRPA1CYP2C9PPARGLMNA
SCHEMBL15301308 0.83 ALDH1A1 (0.48) AKR1C3TRPA1CYP2C9PPARGKMT2A
SCHEMBL7634733 0.83 TRPA1 (0.42) AKR1C3TRPA1CYP2C9PPARGBACE1
SCHEMBL30530 0.82 CYP2C9 (0.51) AKR1C3CYP2C9TBXAS1HTTLMNA
SCHEMBL30528 0.82 CYP2C9 (0.51) AKR1C3CYP2C9TBXAS1HTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530540-B2 Curable composition for imprints, patterning method and pattern FUJIFILM CORPORATION (JP) 2013-09-10 US claimed
US-10570298-B2 Photocurable ink, ink container, and image forming method CANON KABUSHIKI KAISHA (JP) 2020-02-25 US disclosed
US-20180127608-A1 PHOTOCURABLE INK, INK CONTAINER, AND IMAGE FORMING METHOD CANON KABUSHIKI KAISHA (JP) 2018-05-10 US disclosed
US-8820541-B2 Method for producing curable composition for imprints FUJIFILM CORPORATION (JP) 2014-09-02 US disclosed
US-8530540-B2 Curable composition for imprints, patterning method and pattern FUJIFILM CORPORATION (JP) 2013-09-10 US disclosed
US-20120076948-A1 METHOD FOR PRODUCING CURABLE COMPOSITION FOR IMPRINTS FUJIFILM CORPORATION (JP) 2012-03-29 US disclosed
US-20100009287-A1 CURABLE COMPOSITION FOR IMPRINTS, PATTERNING METHOD AND PATTERN FUJIFILM CORPORATION (JP) 2010-01-14 US disclosed