Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.52 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8695659 | 0.96 | ALOX5 (0.47) | ALOX5LTB4R2MLYCDMAOBLTB4R | |
| SCHEMBL8695755 | 0.82 | ALOX5 (0.63) | ALOX5MLYCDMAOBKDM4AKDM5A | |
| SCHEMBL8701009 | 0.80 | ALOX5 (0.46) | ALOX5LTB4R2MLYCDKDM4AKDM5A | |
| SCHEMBL8696461 | 0.78 | ALOX5 (0.56) | ALOX5MLYCDMAOBMAPTNPC1 | |
| SCHEMBL8698886 | 0.77 | CDK4 (0.56) | MAPTNPC1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL8699518 | 0.77 | ALDH1A1 (0.44) | ALOX5LTB4R2MLYCDMAOBKDM4A | |
| SCHEMBL8696569 | 0.76 | ALOX5 (0.46) | ALOX5LTB4R2MLYCDMAOBMAPT | |
| SCHEMBL8010609 | 0.75 | ALOX5 (0.60) | ALOX5MLYCDMAOBKDM4AKDM5A | |
| SCHEMBL17064249 | 0.74 | ALOX5 (0.55) | ALOX5MLYCDMAOBMAPTNPC1 | |
| SCHEMBL2200556 | 0.73 | ALOX5 (0.61) | ALOX5MLYCDMAOBKDM4AKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | claimed |
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |