Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699518 | 0.97 | ALDH1A1 (0.44) | ALOX5MLYCDMAPTNPC1ALDH1A1 | |
| SCHEMBL8695688 | 0.84 | NOX1 (0.36) | MLYCDALDH1A1SMN1; SMN2NPSR1HDAC1 | |
| SCHEMBL8696185 | 0.80 | ALOX5 (0.52) | ALOX5MLYCDMAPTNPC1ALDH1A1 | |
| SCHEMBL8697752 | 0.78 | GOT1 (0.53) | MAPTALDH1A1MAPK1RAB9AKMT2A | |
| SCHEMBL8695755 | 0.77 | ALOX5 (0.63) | ALOX5MLYCDMAPTNPC1ALDH1A1 | |
| SCHEMBL8695659 | 0.77 | ALOX5 (0.47) | ALOX5MLYCDMAPTNPC1ALDH1A1 | |
| SCHEMBL8696594 | 0.76 | NPC1 (0.55) | MAPTNPC1ALDH1A1ALOX15NFKB1 | |
| SCHEMBL15823604 | 0.76 | ALDH1A1 (0.39) | ALOX5MLYCDMAPTNPC1ALDH1A1 | |
| SCHEMBL8696461 | 0.73 | ALOX5 (0.56) | ALOX5MLYCDMAPTNPC1ALDH1A1 | |
| SCHEMBL15822928 | 0.73 | ALDH1A1 (0.39) | ALOX5MLYCDMAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | claimed |
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |