Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701009 | 0.97 | ALOX5 (0.46) | ALDH1A1NPC1RAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL8695688 | 0.85 | NOX1 (0.36) | ALDH1A1SMN1; SMN2MLYCDHDAC1RECQL | |
| SCHEMBL8695659 | 0.80 | ALOX5 (0.47) | ALDH1A1NPC1RAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL8696594 | 0.79 | NPC1 (0.55) | ALDH1A1NPC1RAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL15823604 | 0.79 | ALDH1A1 (0.39) | ALDH1A1NPC1RAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL8697752 | 0.79 | GOT1 (0.53) | ALDH1A1RAB9AMAPTMAPK1KMT2A | |
| SCHEMBL8696185 | 0.77 | ALOX5 (0.52) | ALDH1A1NPC1RAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL8696461 | 0.76 | ALOX5 (0.56) | ALDH1A1NPC1RAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL15822928 | 0.76 | ALDH1A1 (0.39) | ALDH1A1NPC1RAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL8696705 | 0.73 | NPSR1 (0.39) | ALDH1A1SMN1; SMN2MAPTMLYCDHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | claimed |
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |