Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 6/20 | 0.34 |
| ▸ | BRAF | P15056 | 4/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698654 | 0.83 | PTGER1 (0.34) | MEN1KMT2AHDAC1HDAC6ITGB3 | |
| Propionic Acid SCHEMBL8698740 | 0.74 | HDAC1 (0.33) | HDAC1HDAC6ITGB3F10 | |
| SCHEMBL8429316 | 0.71 | ITGB3 (0.39) | MEN1KMT2AITGB3ITGA2B | |
| SCHEMBL8432519 | 0.69 | PTGER4 (0.45) | MEN1KMT2AITGB3ITGA2B | |
| SCHEMBL8428906 | 0.67 | ITGB3 (0.39) | MEN1KMT2AITGB3ITGA2B | |
| SCHEMBL8432900 | 0.67 | PTGER4 (0.40) | MEN1KMT2AHDAC1HDAC6ITGB3 | |
| SCHEMBL8429182 | 0.66 | PTGER4 (0.44) | MEN1KMT2AHDAC1HDAC6ITGB3 | |
| SCHEMBL8429164 | 0.66 | RXFP1 (0.36) | MEN1KMT2AF10 | |
| SCHEMBL8431241 | 0.65 | PTGER4 (0.43) | MEN1KMT2AHDAC1HDAC6ITGB3 | |
| SCHEMBL8432812 | 0.65 | ITGB3 (0.39) | MEN1KMT2AITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843906-A | Meta-substituted phenylene sulphonamide derivatives | G. D. SEARLE & CO. (US) | 1998-12-01 | — | — | US | disclosed |