Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696209 | 0.83 | ATR (0.34) | HDAC6HDAC1ITGB3ITGA2BF10 | |
| SCHEMBL8428906 | 0.76 | ITGB3 (0.39) | PTGER1PTGER4PTGER3PTGER2ITGB3 | |
| SCHEMBL8429316 | 0.76 | ITGB3 (0.39) | PTGER1PTGER4PTGER3PTGER2ITGB3 | |
| SCHEMBL8432900 | 0.75 | PTGER4 (0.40) | PTGER1PTGER4PTGER3PTGER2HDAC6 | |
| SCHEMBL8432519 | 0.75 | PTGER4 (0.45) | PTGER1PTGER4PTGER3PTGER2ITGB3 | |
| Propionic Acid SCHEMBL8698740 | 0.74 | HDAC1 (0.33) | HDAC6HDAC1ITGB3F10 | |
| SCHEMBL8532986 | 0.74 | PTGER4 (0.42) | PTGER1PTGER4PTGER3PTGER2ITGB3 | |
| SCHEMBL8432805 | 0.73 | ITGB3 (0.37) | PTGER1PTGER4PTGER3PTGER2HDAC6 | |
| SCHEMBL8432812 | 0.73 | ITGB3 (0.39) | PTGER1PTGER4PTGER3PTGER2ITGB3 | |
| SCHEMBL8428884 | 0.72 | ITGB3 (0.42) | ITGB3ITGA2BKMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843906-A | Meta-substituted phenylene sulphonamide derivatives | G. D. SEARLE & CO. (US) | 1998-12-01 | — | — | US | disclosed |