Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.52 |
| ▸ | YES1 | P07947 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | JAK3 | P52333 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ICMT | O60725 | 3/20 | 0.51 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20248221 | 0.81 | MEN1 (0.62) | POLBPADI4MEN1KMT2AMAPT | |
| SCHEMBL2006750 | 0.81 | PLA2G4A (0.68) | POLBHDAC6HDAC10PADI4YES1 | |
| SCHEMBL5641773 | 0.80 | HTR6 (0.62) | POLBHDAC6HDAC10YES1KDR | |
| SCHEMBL8701787 | 0.80 | HDAC10 (0.44) | POLBHDAC6HDAC10PADI4YES1 | |
| SCHEMBL4595500 | 0.79 | POLB (0.64) | POLBHDAC6HDAC10PADI4KMT2A | |
| SCHEMBL8289938 | 0.79 | PLA2G2A (0.74) | POLBKMT2AALDH1A1SMN1; SMN2ICMT | |
| SCHEMBL9670003 | 0.79 | POLB (0.60) | POLBHDAC6HDAC10PADI4YES1 | |
| SCHEMBL5329307 | 0.76 | POLB (0.72) | POLBHDAC6HDAC10PADI4HTR6 | |
| Hydrochloric Acid SCHEMBL20605339 | 0.75 | HDAC6 (0.59) | POLBHDAC6HDAC10PADI4KDR | |
| SCHEMBL20248189 | 0.74 | HTR6 (0.62) | POLBHDAC6HDAC10MAPTHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |