Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | YES1 | P07947 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | JAK3 | P52333 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696232 | 0.80 | POLB (0.55) | HDAC10HDAC6YES1KDRJAK3 | |
| SCHEMBL8701532 | 0.76 | ALDH1A1 (0.46) | MEN1KMT2AMAPT | |
| SCHEMBL8698313 | 0.75 | CD274 (0.39) | — | |
| SCHEMBL7382950 | 0.74 | PTGER1 (0.35) | — | |
| SCHEMBL8701536 | 0.73 | HDAC3 (0.51) | HDAC6YES1KDRJAK3MEN1 | |
| SCHEMBL8939296 | 0.72 | PDE4A (0.54) | MEN1KMT2AHTR6 | |
| SCHEMBL8325881 | 0.71 | CHRM1 (0.45) | — | |
| SCHEMBL3320748 | 0.71 | AGTR1 (0.49) | — | |
| SCHEMBL9192715 | 0.71 | CYP11B1 (0.59) | HDAC6POLBHDAC1 | |
| SCHEMBL8328346 | 0.70 | CHRM1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | claimed |