Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FABP3 | P05413 | 3/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696580 | 0.79 | ALDH1A1 (0.46) | KDM4EKMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL8697497 | 0.78 | L3MBTL1 (0.48) | NPC1RAB9AL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL8551756 | 0.76 | CLK1 (0.45) | CLK1NPC1RAB9AFABP4KDM4E | |
| SCHEMBL8552505 | 0.74 | CLK1 (0.44) | CLK1NPC1RAB9AFABP4KDM4E | |
| SCHEMBL8702719 | 0.73 | ALDH1A1 (0.41) | L3MBTL1KDM4EKMT2ARXFP1ALDH1A1 | |
| SCHEMBL8547598 | 0.73 | NPC1 (0.40) | CLK1NPC1RAB9AFABP4KDM4E | |
| SCHEMBL8546890 | 0.73 | EDNRB (0.44) | CLK1NPC1RAB9AFABP4KDM4E | |
| SCHEMBL8697402 | 0.73 | NTRK1 (0.39) | L3MBTL1KDM4EKMT2AALDH1A1HPGD | |
| SCHEMBL8552118 | 0.72 | NPC1 (0.42) | CLK1NPC1RAB9AFABP4KDM4E | |
| SCHEMBL8552363 | 0.72 | NPC1 (0.41) | CLK1NPC1RAB9AFABP4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042709-A1 | ENDOTHELIN-RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 1998-10-01 | — | — | WO | disclosed |