Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696580 | 0.85 | ALDH1A1 (0.46) | MAPTGAAKMT2ALMNASMN1; SMN2 | |
| SCHEMBL8551025 | 0.79 | GAA (0.44) | L3MBTL1MAPTGAAKMT2AATM | |
| SCHEMBL8696358 | 0.78 | CLK1 (0.42) | L3MBTL1PKMKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL8697402 | 0.78 | NTRK1 (0.39) | L3MBTL1MAPTGAAKMT2AHSD17B10 | |
| SCHEMBL8698594 | 0.77 | PTPN1 (0.39) | MAPTGAAKMT2ALMNASMN1; SMN2 | |
| SCHEMBL8697275 | 0.76 | PTPN1 (0.42) | PKMMAPTSMN1; SMN2ADORA2B | |
| SCHEMBL8702719 | 0.75 | ALDH1A1 (0.41) | L3MBTL1MAPTGAAKMT2ALMNA | |
| SCHEMBL8697591 | 0.75 | PTPN1 (0.46) | MAPTGAAKMT2ASMN1; SMN2ADORA2A | |
| SCHEMBL8697633 | 0.75 | POLB (0.37) | KMT2A | |
| SCHEMBL8551848 | 0.74 | CTSV (0.52) | GAAKMT2ATUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042709-A1 | ENDOTHELIN-RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 1998-10-01 | — | — | WO | disclosed |