Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | PRKCA | P17252 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MYLK | Q15746 | 4/20 | 0.37 |
| ▸ | PTGES | O14684 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697633 | 0.88 | POLB (0.37) | GSK3BPRKCAKDM4EMEN1KMT2A | |
| SCHEMBL8697275 | 0.88 | PTPN1 (0.42) | NTRK1GSK3BPRKCAALDH1A1MAPT | |
| SCHEMBL8697591 | 0.87 | PTPN1 (0.46) | GSK3BPRKCAKDM4EALDH1A1MAPT | |
| SCHEMBL8698594 | 0.87 | PTPN1 (0.39) | NTRK1GSK3BPRKCAKDM4EALDH1A1 | |
| SCHEMBL8696580 | 0.87 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL8702544 | 0.85 | EDNRB (0.38) | GSK3BPRKCAKDM4EMEN1KMT2A | |
| SCHEMBL8704430 | 0.82 | EDNRB (0.34) | NTRK1GSK3BPRKCAKDM4EMAPT | |
| SCHEMBL8697497 | 0.78 | L3MBTL1 (0.48) | MAPTKMT2AHSD17B10L3MBTL1GAA | |
| SCHEMBL8702719 | 0.77 | ALDH1A1 (0.41) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL8697199 | 0.74 | EDNRB (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042709-A1 | ENDOTHELIN-RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 1998-10-01 | — | — | WO | disclosed |