Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | STS | P08842 | 3/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693738 | 0.89 | HPGD (0.52) | ALDH1A1SMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL8698799 | 0.87 | MAPT (0.50) | ALDH1A1SMN1; SMN2MAPK1NPC1RAB9A | |
| SCHEMBL8693781 | 0.84 | RAB9A (0.47) | ALDH1A1SMN1; SMN2KMT2AMAPK1NPC1 | |
| SCHEMBL8696400 | 0.83 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL8695922 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KMT2ACNR1CNR2 | |
| SCHEMBL8696733 | 0.77 | KMT2A (0.46) | ALDH1A1SMN1; SMN2KMT2AMAPK1RAB9A | |
| SCHEMBL8696204 | 0.77 | FAAH (0.48) | ALDH1A1SMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL6312199 | 0.75 | ALDH1A1 (0.50) | ALDH1A1KMT2ANPC1RAB9AGAA | |
| SCHEMBL8692678 | 0.75 | HTT (0.46) | ALDH1A1SMN1; SMN2KMT2ALMNAALOX12 | |
| SCHEMBL8696777 | 0.74 | POLB (0.44) | ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849779-A | Pyrazole derivatives and their pharmaceutical use | JAPAN ENERGY CORPORATION (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0810217-A1 | Pyrazole derivatives and their pharmaceutical use as smooth muscle cell growth inhibitors | JAPAN ENERGY CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |