Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696204 | 0.91 | FAAH (0.48) | ALDH1A1FAAHLMNATDP1NPC1 | |
| SCHEMBL8696364 | 0.87 | ALDH1A1 (0.49) | ALDH1A1LMNAALOX12GAANPC1 | |
| SCHEMBL8692959 | 0.87 | MAPT (0.54) | MAPTALDH1A1FAAHLMNAALOX12 | |
| SCHEMBL8696385 | 0.85 | MAPT (0.52) | MAPTALDH1A1FAAHLMNATDP1 | |
| SCHEMBL14542033 | 0.85 | PDE4B (0.49) | MAPTALDH1A1FAAHLMNANPC1 | |
| SCHEMBL8692971 | 0.84 | ALDH1A1 (0.42) | ALDH1A1FAAHLMNATDP1GAA | |
| SCHEMBL8693117 | 0.84 | MAPT (0.50) | MAPTALDH1A1FAAHLMNATDP1 | |
| SCHEMBL8693790 | 0.83 | ALDH1A1 (0.44) | MAPTALDH1A1FAAHLMNATDP1 | |
| SCHEMBL8695938 | 0.82 | ALDH1A1 (0.47) | MAPTALDH1A1LMNAALOX12GAA | |
| SCHEMBL8694236 | 0.80 | ALDH1A1 (0.46) | MAPTALDH1A1LMNAALOX12GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849779-A | Pyrazole derivatives and their pharmaceutical use | JAPAN ENERGY CORPORATION (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0810217-A1 | Pyrazole derivatives and their pharmaceutical use as smooth muscle cell growth inhibitors | JAPAN ENERGY CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |