Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 6/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5980742 | 0.81 | FKBP1A (0.42) | SMN1; SMN2CYP2C19FKBP1ADPP4KCNH2 | |
| SCHEMBL8554808 | 0.75 | DPP4 (0.44) | SMN1; SMN2CYP2C19FKBP1ADPP4KCNH2 | |
| SCHEMBL8923888 | 0.72 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP2C19DPP4KCNH2DPP7 | |
| SCHEMBL10343310 | 0.71 | FKBP1A (0.61) | FKBP1APREPTSHR | |
| SCHEMBL18806512 | 0.71 | FKBP1A (0.61) | FKBP1APREPTSHR | |
| SCHEMBL8790582 | 0.71 | CYP2C19 (0.41) | SMN1; SMN2CYP2C19DPP4KCNH2DPP7 | |
| SCHEMBL8790127 | 0.71 | CYP2C19 (0.41) | SMN1; SMN2CYP2C19DPP4KCNH2DPP7 | |
| Hydrochloric Acid SCHEMBL8040977 | 0.70 | FKBP1A (0.60) | FKBP1APREPTSHR | |
| Hydrochloric Acid SCHEMBL11217224 | 0.70 | FKBP1A (0.60) | FKBP1APREPTSHR | |
| SCHEMBL2135198 | 0.68 | ALDH1A1 (0.60) | CYP2C19ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741799-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| US-4703036-A | ANTICOAGULANTS | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-10-27 | — | — | US | disclosed |