Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697533 | 0.88 | ALDH1A1 (0.44) | ACLYKMT2AHPGDALDH1A1KDM4E | |
| SCHEMBL9122659 | 0.83 | PSIP1 (0.43) | KMT2AHPGDALDH1A1KDM4ECA1 | |
| SCHEMBL8696399 | 0.81 | KMT2A (0.48) | ACLYKMT2AHPGDALDH1A1KDM4E | |
| SCHEMBL8697664 | 0.77 | VCAM1 (0.44) | ACLYKMT2AALDH1A1MAPK1PTK2B | |
| SCHEMBL22315270 | 0.76 | KMT2A (0.59) | ACLYKMT2AHPGDALDH1A1KDM4E | |
| SCHEMBL26075685 | 0.73 | KMT2A (0.48) | ACLYKMT2AHPGDALDH1A1KDM4E | |
| SCHEMBL9427577 | 0.72 | HPGD (0.45) | KMT2AHPGDALDH1A1CA1CA2 | |
| SCHEMBL7589006 | 0.72 | ALDH1A1 (0.50) | ACLYKMT2AHPGDALDH1A1KDM4E | |
| SCHEMBL6197105 | 0.71 | CA1 (0.43) | KMT2AHPGDALDH1A1CA1CA2 | |
| SCHEMBL9120354 | 0.71 | ALDH1A1 (0.46) | KMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998028280-A1 | CERTAIN 3-[2,4-DISUBSTITUTED-5-(SUBSTITUTED AMINO)PHENYL]-1-SUBSTITUTED-6-TRIFLUOROMETHYL-2,4-(1H,3H)-PYRIMIDINEDIONE DERIVATIVES AS HERBICIDES | FMC CORPORATION (US) | 1998-07-02 | — | — | WO | disclosed |