Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698664 | 0.91 | RAB9A (0.45) | RAB9ASMN1; SMN2NPC1KMT2AEPHX1 | |
| SCHEMBL8693781 | 0.88 | RAB9A (0.47) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL8692495 | 0.86 | RAB9A (0.54) | RAB9ASMN1; SMN2NPC1KMT2AEPHX2 | |
| SCHEMBL8693738 | 0.84 | HPGD (0.52) | RAB9ASMN1; SMN2NPC1KMT2AEPHX1 | |
| SCHEMBL8696400 | 0.79 | ALDH1A1 (0.45) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL8695922 | 0.78 | ALDH1A1 (0.43) | KMT2AMEN1 | |
| SCHEMBL8696502 | 0.78 | RAB9A (0.44) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL8698684 | 0.76 | CNR2 (0.43) | RAB9ASMN1; SMN2NPC1KMT2AEPHX1 | |
| SCHEMBL8696204 | 0.76 | FAAH (0.48) | RAB9ASMN1; SMN2NPC1KMT2AEPHX1 | |
| SCHEMBL8696424 | 0.76 | SMN1; SMN2 (0.40) | RAB9ASMN1; SMN2NPC1KMT2AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849779-A | Pyrazole derivatives and their pharmaceutical use | JAPAN ENERGY CORPORATION (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0810217-A1 | Pyrazole derivatives and their pharmaceutical use as smooth muscle cell growth inhibitors | JAPAN ENERGY CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |