Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.43 |
| ▸ | CNR1 | P21554 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696502 | 0.94 | RAB9A (0.44) | CNR2CNR1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8693117 | 0.90 | MAPT (0.50) | CNR2CNR1RAB9ANPC1FAAH | |
| SCHEMBL8692495 | 0.89 | RAB9A (0.54) | RAB9ASMN1; SMN2EPHX2NPC1FAAH | |
| SCHEMBL8697628 | 0.87 | EPHX1 (0.45) | CNR2CNR1RAB9ASMN1; SMN2EPHX1 | |
| SCHEMBL8693502 | 0.84 | ALDH1A1 (0.46) | CNR2CNR1RAB9ANPC1MEN1 | |
| SCHEMBL8696385 | 0.84 | MAPT (0.52) | CNR2CNR1RAB9ANPC1FAAH | |
| SCHEMBL8696204 | 0.83 | FAAH (0.48) | CNR2CNR1RAB9ASMN1; SMN2EPHX1 | |
| SCHEMBL8694014 | 0.81 | ALDH1A1 (0.42) | CNR2CNR1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8693098 | 0.81 | HTT (0.43) | RAB9ASMN1; SMN2NPC1KMT2ANPSR1 | |
| SCHEMBL8698664 | 0.81 | RAB9A (0.45) | CNR2CNR1RAB9ASMN1; SMN2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849779-A | Pyrazole derivatives and their pharmaceutical use | JAPAN ENERGY CORPORATION (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0810217-A1 | Pyrazole derivatives and their pharmaceutical use as smooth muscle cell growth inhibitors | JAPAN ENERGY CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |