Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690404 | 0.81 | AGTR1 (0.42) | — | |
| SCHEMBL9060804 | 0.74 | LTB4R2 (0.44) | LTB4R2 | |
| SCHEMBL8695037 | 0.67 | AGTR1 (0.44) | — | |
| SCHEMBL7051555 | 0.66 | SLC6A3 (0.58) | SLC6A3SLC6A4SLC6A2MAPTTSHR | |
| SCHEMBL9427527 | 0.65 | AGTR1 (0.49) | SLC6A3SLC6A4MAPTLTB4R2 | |
| SCHEMBL9429975 | 0.65 | SMN1; SMN2 (0.55) | SLC6A3SLC6A4MAPTL3MBTL1LTB4R2 | |
| SCHEMBL20928284 | 0.65 | SLC6A3 (0.57) | SLC6A3SLC6A4SLC6A2MAPK1MAPT | |
| SCHEMBL7984003 | 0.64 | ERN1 (0.65) | SLC6A3SLC6A4SLC6A2MAPTTSHR | |
| SCHEMBL4742997 | 0.64 | TSHR (0.57) | SLC6A3SLC6A4SLC6A2MAPK1MAPT | |
| SCHEMBL28486252 | 0.64 | SLC6A3 (0.57) | SLC6A3SLC6A4SLC6A2MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827863-A | Pyrazole derivatives as angiotensin II antagonists | J. URIACH & CIA, S.A. (ES) | 1998-10-27 | — | — | US | disclosed |