Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | USP7 | Q93009 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696644 | 0.76 | CPB2 (0.35) | USP7 | |
| SCHEMBL8697303 | 0.69 | GABRP (0.38) | KDM4EGAAALDH1A1HSD17B10 | |
| SCHEMBL23888650 | 0.69 | CSNK1A1 (0.41) | USP7HTTCSNK1A1CLK4KDM4E | |
| SCHEMBL7898980 | 0.68 | HTT (0.44) | HTTCSNK1A1CLK4KDM4EGAA | |
| SCHEMBL245286 | 0.66 | HTT (0.62) | HTTCSNK1A1CLK4KDM4EGAA | |
| SCHEMBL7898395 | 0.65 | HTT (0.41) | HTTCSNK1A1CLK4KDM4EGAA | |
| SCHEMBL921763 | 0.65 | KHK (0.43) | HTTCSNK1A1CLK4KDM4EGAA | |
| SCHEMBL322329 | 0.65 | HTT (0.54) | HTTCSNK1A1CLK4KDM4EGAA | |
| SCHEMBL31695297 | 0.65 | NOS3 (0.54) | HTTCSNK1A1CLK4KDM4EGAA | |
| SCHEMBL30937717 | 0.65 | KHK (0.43) | HTTCSNK1A1CLK4KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767133-A | Secondary amines as antidiabetic and antiobesity agents | PFIZER INC. (US) | 1998-06-16 | — | — | US | disclosed |