SCHEMBL8696644

SCHEMBL8696644

Nc1ncc([N]CCO)cc1Cl

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 3/20 0.35
USP7 Q93009 1/20 0.31
SCNN1A P37088 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8696946 0.76 CCNA2 (0.34) USP7
SCHEMBL8697303 0.69 GABRP (0.38) CPB2
SCHEMBL9649790 0.68 CPB2 (0.50) CPB2USP7
SCHEMBL31483402 0.65
SCHEMBL7411078 0.65
SCHEMBL30838764 0.64
SCHEMBL27957344 0.64 PLAU (0.47) CPB2
SCHEMBL120637 0.64
SCHEMBL3603993 0.64
SCHEMBL8696375 0.63 HTR3E (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5767133-A Secondary amines as antidiabetic and antiobesity agents PFIZER INC. (US) 1998-06-16 US disclosed