Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | MMP15 | P51511 | 1/20 | 0.41 |
| ▸ | MMP16 | P51512 | 1/20 | 0.41 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8702479 | 0.92 | KMT2A (0.42) | MMP2MMP9MMP12MMP14MMP15 | |
| SCHEMBL8696621 | 0.89 | G6PD (0.41) | MMP2MMP9MMP12MMP14MMP15 | |
| SCHEMBL8702949 | 0.89 | MMP2 (0.40) | MMP2MMP9MMP12MMP14MMP15 | |
| SCHEMBL8702048 | 0.89 | MMP2 (0.40) | MMP2MMP9MMP12MMP14MMP15 | |
| SCHEMBL8696159 | 0.86 | KMT2A (0.44) | MMP2MMP9MMP12MMP14MMP15 | |
| SCHEMBL8700342 | 0.84 | MAOB (0.40) | MMP2MMP9MMP12MMP14MMP15 | |
| SCHEMBL8700018 | 0.84 | ALDH1A1 (0.41) | MMP2MMP9MMP12MMP14MMP15 | |
| SCHEMBL8698014 | 0.82 | MAPT (0.41) | MMP2MMP9MMP12MMP14MMP15 | |
| SCHEMBL8697830 | 0.81 | KMT2A (0.41) | KMT2AMEN1CES2CES1ALDH1A1 | |
| SCHEMBL8696162 | 0.81 | MAOB (0.43) | MMP2MMP9MMP12MMP14MMP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998003478-A1 | NITRONE DERIVATIVES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-01-29 | — | — | WO | disclosed |
| WO-1998003479-A1 | NITRONE DERIVATIVES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-01-29 | — | — | WO | disclosed |