Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 4/20 | 0.36 |
| ▸ | CES1 | P23141 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8702479 | 0.89 | KMT2A (0.42) | MAPTHTTRAB9AATMNPC1 | |
| SCHEMBL8697105 | 0.82 | MMP2 (0.41) | MAPTHTTRAB9AATMNPC1 | |
| SCHEMBL8702949 | 0.81 | MMP2 (0.40) | MAPTRAB9ANPC1SLC6A2SLC6A3 | |
| SCHEMBL8702048 | 0.81 | MMP2 (0.40) | MAPTHTTALDH1A1KMT2AADRA2B | |
| SCHEMBL8700342 | 0.81 | MAOB (0.40) | MAPTHTTRAB9AATMNPC1 | |
| SCHEMBL8700018 | 0.81 | ALDH1A1 (0.41) | MAPTHTTRAB9AATMNPC1 | |
| SCHEMBL8696621 | 0.81 | G6PD (0.41) | MAPTHTTATMALDH1A1KMT2A | |
| SCHEMBL8697830 | 0.80 | KMT2A (0.41) | ALDH1A1KMT2ACES2CES1PRMT1 | |
| SCHEMBL8696553 | 0.80 | ALDH1A1 (0.44) | MAPTHTTRAB9AATMNPC1 | |
| SCHEMBL8696159 | 0.79 | KMT2A (0.44) | MAPTHTTRAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998003479-A1 | NITRONE DERIVATIVES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-01-29 | — | — | WO | disclosed |