Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | DAO | P14920 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578072 | 0.79 | KMT2A (0.76) | KMT2AL3MBTL1DAOLMNAHTT | |
| SCHEMBL29115280 | 0.76 | HPGD (0.60) | KMT2AL3MBTL1FABP4SMN1; SMN2ALDH1A1 | |
| SCHEMBL8019843 | 0.73 | KDM4E (0.45) | KMT2ALMNAGPR84ALDH1A1MEN1 | |
| SCHEMBL8803221 | 0.71 | ALDH1A1 (0.45) | KMT2ALMNASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL10048200 | 0.70 | LMNA (0.54) | KMT2AL3MBTL1LMNAHTTGPR84 | |
| SCHEMBL7679940 | 0.68 | ALDH1A1 (0.77) | KMT2AL3MBTL1LMNAHTTMTNR1A | |
| SCHEMBL8581796 | 0.68 | DAO (0.55) | KMT2AL3MBTL1DAOLMNAHTT | |
| SCHEMBL8698658 | 0.68 | DAO (0.49) | KMT2ADAOLMNAALDH1A1HPGD | |
| SCHEMBL8129531 | 0.68 | HCAR1 (0.38) | KMT2AL3MBTL1LMNAHTTFABP4 | |
| SCHEMBL1527275 | 0.67 | LMNA (0.40) | KMT2ALMNAHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998040362-A1 | SUBSTITUTED ARYLALKYLURACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-17 | — | — | WO | disclosed |