Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8702570 | 0.85 | DAO (0.48) | DAOMEN1KMT2ABRAFLMNA | |
| SCHEMBL8993633 | 0.69 | MEN1 (0.39) | MEN1KMT2ABRAFALDH1A1HPGD | |
| SCHEMBL8697133 | 0.68 | KMT2A (0.48) | DAOMEN1KMT2ABRAFALDH1A1 | |
| SCHEMBL2673303 | 0.63 | NR3C1 (0.48) | DAOMEN1KMT2AHPGDMAOB | |
| SCHEMBL16028820 | 0.62 | ATM (0.71) | MEN1KMT2ABRAFATMAPOBEC3G | |
| SCHEMBL16028621 | 0.62 | ATM (0.71) | MEN1KMT2ABRAFATMAPOBEC3G | |
| SCHEMBL15922546 | 0.62 | KMT2A (0.56) | DAOMEN1KMT2ABRAFATM | |
| SCHEMBL8581796 | 0.62 | DAO (0.55) | DAOMEN1KMT2ABRAFALDH1A1 | |
| SCHEMBL2135113 | 0.61 | TAAR1 (0.68) | DAOMAOBLMNA | |
| SCHEMBL18834071 | 0.61 | KMT2A (0.44) | DAOMEN1KMT2ABRAFATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998040362-A1 | SUBSTITUTED ARYLALKYLURACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-17 | — | — | WO | disclosed |