SCHEMBL8697137

SCHEMBL8697137

ClCCOCCO[CH]c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.30
ALDH1A1 P00352 1/20 0.30
PTK2B Q14289 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8341640 0.81 RELA (0.39) KMT2AMEN1LMNASMN1; SMN2ALDH1A1
SCHEMBL28514854 0.81 KMT2A (0.42) KMT2AMEN1LMNASMN1; SMN2ALDH1A1
SCHEMBL3657712 0.80 KCNA3 (0.38)
SCHEMBL8340935 0.78 RELA (0.40) KMT2AMEN1SMN1; SMN2ALDH1A1
SCHEMBL8333879 0.77 TSHR (0.52) LMNASMN1; SMN2ALDH1A1
SCHEMBL7054866 0.74 ALDH1A1 (0.36) KMT2AMEN1LMNAALDH1A1
SCHEMBL2122339 0.74 MEN1 (0.44) KMT2AMEN1LMNASMN1; SMN2ALDH1A1
SCHEMBL815747 0.71 MEN1 (0.39) KMT2AMEN1LMNAALDH1A1
SCHEMBL635906 0.71 TAAR1 (0.46) KMT2AMEN1SMN1; SMN2ALDH1A1
SCHEMBL790516 0.71 ALDH1A1 (0.46) KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5840684-A Glycopeptide antibiotic derivatives ELI LILLY AND COMPANY (US) 1998-11-24 US disclosed