Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL815747 | 0.77 | MEN1 (0.39) | KDM4EHPGDCYP3A4MEN1ALDH1A1 | |
| SCHEMBL790516 | 0.77 | ALDH1A1 (0.46) | CYP19A1ESR1ESR2MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9443692 | 0.77 | IDO1 (0.46) | TAAR1CYP19A1ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL9443690 | 0.77 | IDO1 (0.46) | TAAR1CYP19A1ESR1ESR2KDM4E | |
| SCHEMBL2122339 | 0.76 | MEN1 (0.44) | KDM4EMAPK1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL9798232 | 0.75 | ALDH1A1 (0.39) | KDM4EHPGDCYP3A4ALDH1A1TSHR | |
| SCHEMBL3657712 | 0.74 | KCNA3 (0.38) | IDO1 | |
| SCHEMBL317685 | 0.74 | LTA4H (0.47) | KDM4EHPGDMEN1ALDH1A1CYP1A2 | |
| SCHEMBL8340935 | 0.72 | RELA (0.40) | KDM4EHPGDMEN1ALDH1A1CYP1A2 | |
| SCHEMBL662842 | 0.72 | CYP19A1 (0.45) | TAAR1CYP19A1ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060178-B1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ROTAMASE ENZYMES | PFIZER (US) | 2003-09-03 | — | — | EP | claimed |
| US-6610707-B1 | Moderate neuronal regeneration and outgrowth and can be used for treating neurological disorders arising from neurodegenerative diseases and nerve damage. | PFIZER INC. | 2003-08-26 | — | — | US | claimed |
| EP-1060178-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ROTAMASE ENZYMES | PFIZER INC. (US) | 2000-12-20 | — | — | EP | claimed |
| WO-1999045006-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ROTAMASE ENZYMES | PFIZER INC. (US) | 1999-09-10 | — | — | WO | claimed |
| US-20120253038-A1 | PROCESSES FOR THE SYNTHESIS OF BAZEDOXIFENE ACETATE AND INTERMEDIATES THEREOF | SANDOZ AG (CH) | 2012-10-04 | — | — | US | disclosed |
| EP-2419406-A1 | PROCESSES FOR THE SYNTHESIS OF BAZEDOXIFENE ACETATE AND INTERMEDIATES THEREOF | Sandoz AG (CH) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010118997-A1 | PROCESSES FOR THE SYNTHESIS OF BAZEDOXIFENE ACETATE AND INTERMEDIATES THEREOF | SANDOZ AG (CH) | 2010-10-21 | — | — | WO | disclosed |
| US-20080207898-A1 | PROCESSES FOR THE PREPARATION OF AMINOETHOXYBENZYL ALCOHOLS | WYETH (US) | 2008-08-28 | — | — | US | disclosed |
| US-20080207898-A1 | PROCESSES FOR THE PREPARATION OF AMINOETHOXYBENZYL ALCOHOLS | WYETH (US) | 2008-08-28 | — | — | US | disclosed |
| US-7375251-B2 | Processes for the preparation of aminoethoxybenzyl alcohols | WYETH (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375251-B2 | Processes for the preparation of aminoethoxybenzyl alcohols | WYETH (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375251-B2 | Processes for the preparation of aminoethoxybenzyl alcohols | WYETH (US) | 2008-05-20 | — | — | US | disclosed |
| WO-2006076350-A2 | PROCESSES FOR THE PREPARATION OF AMINOETHOXYBENZYL ALCOHOLS | WYETH (US) | 2006-07-20 | — | — | WO | disclosed |
| US-20060155147-A1 | Processes for the preparation of aminoethoxybenzyl alcohols | WYETH (US) | 2006-07-13 | — | — | US | disclosed |
| US-20060155147-A1 | Processes for the preparation of aminoethoxybenzyl alcohols | WYETH (US) | 2006-07-13 | — | — | US | disclosed |
| US-20060155147-A1 | Processes for the preparation of aminoethoxybenzyl alcohols | WYETH (US) | 2006-07-13 | — | — | US | disclosed |
| EP-1060178-B1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ROTAMASE ENZYMES | PFIZER (US) | 2003-09-03 | — | — | EP | disclosed |
| US-6610707-B1 | Moderate neuronal regeneration and outgrowth and can be used for treating neurological disorders arising from neurodegenerative diseases and nerve damage. | PFIZER INC. | 2003-08-26 | — | — | US | disclosed |
| EP-1060178-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ROTAMASE ENZYMES | PFIZER INC. (US) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999045006-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ROTAMASE ENZYMES | PFIZER INC. (US) | 1999-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207898-A1 | PROCESSES FOR THE PREPARATION OF AMINOETHOXYBENZYL ALCOHOLS | ADH1A, ADH1C, ADH5 | TAAR1 307/4885CYP19A1 395/4885ESR1 4010/4885 |
| US-20060155147-A1 | Processes for the preparation of aminoethoxybenzyl alcohols | ADH1A, ADH1C, ADH5 | TAAR1 307/4885CYP19A1 395/4885ESR1 4010/4885 |
| US-20120253038-A1 | PROCESSES FOR THE SYNTHESIS OF BAZEDOXIFENE ACETATE AND INTERMEDIATES THEREOF | CYP19A1, HSD17B11, CYP2F1 | TAAR1 1627/4885CYP19A1 1/4885ESR1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.