Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL8697383

CNC(=O)[C@@H](N)C(C)(C)SC.O=C(O)C(F)(F)F

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.31
DPP8 Q6V1X1 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
PTGS1 P23219 1/20 0.31
CHIT1 Q13231 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6670760 0.89 DPP4 (0.32) DPP4ALDH1A1MAPTPTGS1
Trifluoroacetic Acid SCHEMBL7399856 0.82 DPP4 (0.42) DPP4DPP8ALDH1A1MAPTPTGS1
SCHEMBL12867478 0.73 MAPT (0.34) DPP4DPP8ALDH1A1MAPTPTGS1
SCHEMBL8426774 0.73 MAPT (0.34) DPP4DPP8ALDH1A1MAPTPTGS1
SCHEMBL8202933 0.73 MAPT (0.34) DPP4DPP8ALDH1A1MAPTPTGS1
Hydrochloric Acid SCHEMBL1174259 0.71 DPP4 (0.33) DPP4DPP8ALDH1A1MAPTPTGS1
SCHEMBL19009024 0.71 MAPT (0.31) DPP4ALDH1A1MAPTPTGS1
SCHEMBL17617087 0.71 MAPT (0.31) DPP4ALDH1A1MAPTPTGS1
SCHEMBL25600609 0.71 MAPT (0.31) DPP4ALDH1A1MAPTPTGS1
SCHEMBL7418366 0.71 ALDH1A1 (0.52) ALDH1A1MAPTPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5714491-A ANTICANCER AND ANTITUMOR AGENT CELLTECH THERAPEUTICS LIMITED (GB) 1998-02-03 US disclosed