Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 12/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.73 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8694224 | 0.83 | MEN1 (0.64) | MEN1KMT2AHCRTR1GAACYP3A4 | |
| SCHEMBL8716448 | 0.83 | KMT2A (0.64) | MEN1KMT2AHCRTR1GAAMAPT | |
| SCHEMBL8660441 | 0.82 | MEN1 (0.50) | MEN1KMT2AHCRTR1GAACYP3A4 | |
| SCHEMBL8672827 | 0.79 | MEN1 (0.48) | MEN1KMT2AHCRTR1GAACYP3A4 | |
| SCHEMBL7163580 | 0.75 | MEN1 (0.55) | MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL9013774 | 0.73 | MEN1 (0.60) | MEN1KMT2AHCRTR1GAACYP3A4 | |
| SCHEMBL9013742 | 0.73 | MEN1 (0.46) | MEN1KMT2AHCRTR1GAACYP3A4 | |
| SCHEMBL8711149 | 0.72 | KMT2A (0.59) | MEN1KMT2AGAAMAPTLMNA | |
| SCHEMBL8300463 | 0.72 | LMNA (0.57) | MEN1KMT2AGAAMAPTLMNA | |
| SCHEMBL8585347 | 0.71 | KMT2A (0.53) | MEN1KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5783707-A | ANTICHOLESTEROL AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-07-21 | — | — | US | claimed |
| US-5783707-A | ANTICHOLESTEROL AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-07-21 | — | — | US | disclosed |
| US-5554607-A | INCREASING HDL CHOLESTEROL | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |