Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.39 |
| ▸ | PPARG | P37231 | 7/20 | 0.39 |
| ▸ | PPARD | Q03181 | 7/20 | 0.39 |
| ▸ | PPARA | Q07869 | 7/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL546145 | 1.00 | CES2 (0.40) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL5176057 | 0.90 | CES2 (0.39) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL29209162 | 0.84 | CES2 (0.41) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL3458239 | 0.84 | MEN1 (0.33) | ALDH1A1MEN1KMT2A | |
| SCHEMBL10398719 | 0.83 | FDPS (0.39) | CES2GGPS1 | |
| SCHEMBL16093651 | 0.82 | TERT (0.51) | PPARGPPARDPPARAPTPN1TDP1 | |
| SCHEMBL16093648 | 0.82 | TERT (0.51) | PPARGPPARDPPARAPTPN1TDP1 | |
| SCHEMBL9723993 | 0.81 | DNM1 (0.41) | TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL10686786 | 0.81 | FDPS (0.39) | TSHRALDH1A1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL27767039 | 0.80 | FDPS (0.38) | TSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2613772-B1 | LOW-DOSE TRANSDERMAL PATCHES WITH HIGH DRUG RELEASE | BAYER IP GMBH (DE) | 2016-12-14 | — | — | EP | disclosed |
| US-9005653-B2 | Transdermal delivery of hormones with low concentration of penetration enhancers | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-04-14 | — | — | US | disclosed |
| US-20140109916-A1 | Transdermal Delivery of Hormones without the Need of Penetration Enhancers | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-04-24 | — | — | US | disclosed |
| US-8671945-B2 | Low-dose transdermal patches with high drug release | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-03-18 | — | — | US | disclosed |
| US-8668925-B2 | Transdermal delivery of hormones without the need of penetration enhancers | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-03-11 | — | — | US | disclosed |
| EP-2138169-B1 | Transdermal delivery system of hormones without penetration enhancers | BAYER IP GMBH (DE) | 2013-11-06 | — | — | EP | disclosed |
| US-20120073578-A1 | LOW-DOSE TRANSDERMAL PATCHES WITH HIGH DRUG RELEASE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-29 | — | — | US | disclosed |
| EP-2138169-A2 | Transdermal delivery system of hormones without penetration enhancers | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-12-30 | — | — | EP | disclosed |
| WO-2005058287-A2 | TRANSDERMAL DELIVERY SYSTEM OF HORMONES WITHOUT PENETRATION ENHANCERS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-06-30 | — | — | WO | disclosed |
| US-20050142175-A1 | Transdermal delivery of hormones without the need of penetration enhancers | LUYE PHARMA SWITZERLAND AG (CH) | 2005-06-30 | — | — | US | disclosed |
| EP-1541137-A2 | Transdermal delivery system of hormones without penetration enhancers | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-06-15 | — | — | EP | disclosed |