Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | PRCP | P42785 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 4/20 | 0.41 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.41 |
| ▸ | PDE6D | O43924 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696612 | 0.89 | BLM (0.61) | BLMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8701038 | 0.85 | NPC1 (0.54) | BLMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8697813 | 0.85 | NPC1 (0.51) | BLMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8699491 | 0.83 | NPC1 (0.62) | BLMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8702971 | 0.82 | PTGS2 (0.50) | BLMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8698720 | 0.81 | BLM (0.61) | BLMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8701544 | 0.81 | NPC1 (0.53) | BLMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8541896 | 0.81 | FAAH (0.56) | NPC1MEN1KMT2AESR1TDP1 | |
| SCHEMBL8699125 | 0.80 | ESR1 (0.42) | MEN1KMT2AESR1NPSR1 | |
| SCHEMBL8696494 | 0.79 | NPC1 (0.53) | BLMNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741800-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | KNOLL AKTIENGESELLACHAFT (DE) | 1998-04-21 | — | — | US | disclosed |