Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696612 | 0.88 | BLM (0.61) | NPC1RAB9AKMT2AMEN1BLM | |
| SCHEMBL8697813 | 0.86 | NPC1 (0.51) | NPC1RAB9AKMT2AMEN1BLM | |
| SCHEMBL8698349 | 0.85 | BLM (0.52) | NPC1RAB9AKMT2AMEN1BLM | |
| SCHEMBL8699491 | 0.83 | NPC1 (0.62) | NPC1RAB9AKMT2AMEN1BLM | |
| SCHEMBL8539166 | 0.81 | GRIN2B (0.54) | NPC1KMT2AMEN1HPGDTDP1 | |
| SCHEMBL8698720 | 0.80 | BLM (0.61) | NPC1RAB9AKMT2AMEN1BLM | |
| SCHEMBL8701544 | 0.80 | NPC1 (0.53) | NPC1RAB9AKMT2AMEN1BLM | |
| SCHEMBL8699588 | 0.80 | ALDH1A1 (0.42) | NPC1RAB9AKMT2AMEN1NPSR1 | |
| SCHEMBL14646631 | 0.80 | NPC1 (0.70) | NPC1RAB9AKMT2AMEN1HPGD | |
| SCHEMBL8696494 | 0.78 | NPC1 (0.53) | NPC1RAB9AKMT2AMEN1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741800-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | KNOLL AKTIENGESELLACHAFT (DE) | 1998-04-21 | — | — | US | disclosed |