Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696612 | 0.94 | BLM (0.61) | NPC1RAB9AMEN1KMT2ABLM | |
| SCHEMBL8698720 | 0.86 | BLM (0.61) | NPC1RAB9AMEN1KMT2ABLM | |
| SCHEMBL8698349 | 0.83 | BLM (0.52) | NPC1RAB9AMEN1KMT2ABLM | |
| SCHEMBL8701038 | 0.83 | NPC1 (0.54) | NPC1RAB9AMEN1KMT2ABLM | |
| SCHEMBL8697813 | 0.82 | NPC1 (0.51) | NPC1RAB9AMEN1KMT2ABLM | |
| SCHEMBL8701671 | 0.82 | ADRA2A (0.42) | MEN1KMT2ABLM | |
| SCHEMBL8545094 | 0.81 | F10 (0.57) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL8701243 | 0.80 | NPC1 (0.62) | NPC1RAB9AMEN1KMT2AHPGD | |
| SCHEMBL8701544 | 0.78 | NPC1 (0.53) | NPC1RAB9AMEN1KMT2ABLM | |
| SCHEMBL8699938 | 0.77 | NPC1 (0.54) | NPC1RAB9AMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741800-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | KNOLL AKTIENGESELLACHAFT (DE) | 1998-04-21 | — | — | US | disclosed |