SCHEMBL8993633

SCHEMBL8993633

Cn1c(C(F)(F)F)c(-c2ccc(Cl)cc2)c(=S)[nH]c1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
BRAF P15056 1/20 0.38
KCNQ3 O43525 2/20 0.36
KCNQ2 O43526 2/20 0.36
PSD A5PKW4 1/20 0.36
LMNA P02545 3/20 0.36
HTT P42858 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 1/20 0.36
S1PR2 O95136 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
GLP1R P43220 1/20 0.36
RAB9A P51151 1/20 0.36
GAA P10253 3/20 0.35
MAPT P10636 3/20 0.35
PGR P06401 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8698658 0.69 DAO (0.49) MEN1KMT2ABRAFLMNAMAPT
SCHEMBL9359135 0.66 GRIK1 (0.50) MEN1KMT2ALMNAGAAMAPT
SCHEMBL16831341 0.64 GRIA4 (0.46) MEN1KMT2AHTTSMN1; SMN2NPC1
SCHEMBL5775226 0.64 HTT (0.42) KCNQ3KCNQ2PSDLMNAHTT
SCHEMBL5773450 0.64 LIPG (0.44) MEN1KMT2AKCNQ3KCNQ2PSD
SCHEMBL5776146 0.63 LIPG (0.43) MEN1KMT2AKCNQ3KCNQ2PSD
SCHEMBL7545703 0.63 KMT2A (0.52) MEN1KMT2ABRAFSMN1; SMN2NPC1
SCHEMBL25232301 0.61 DDR1 (0.36) MEN1KMT2ABRAFLMNASMN1; SMN2
SCHEMBL31172135 0.61 DDR1 (0.36) MEN1KMT2ABRAFLMNASMN1; SMN2
SCHEMBL30940103 0.61 KMO (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5527764-A 3-arylthionouracils useful as herbicides, defoliants, and desiccants UNIROYAL CHEMICAL COMPANY, INC. (US) 1996-06-18 US disclosed