Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693117 | 0.94 | MAPT (0.50) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL8692959 | 0.92 | MAPT (0.54) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL8696502 | 0.90 | RAB9A (0.44) | MAPTALDH1A1MEN1KMT2AFAAH | |
| SCHEMBL8696400 | 0.87 | ALDH1A1 (0.45) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL8698799 | 0.85 | MAPT (0.50) | MAPTALDH1A1FAAHLMNAGAA | |
| SCHEMBL8698684 | 0.84 | CNR2 (0.43) | ALDH1A1MEN1KMT2AFAAHLMNA | |
| SCHEMBL8698701 | 0.83 | ALDH1A1 (0.43) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8695922 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ACNR1CNR2 | |
| SCHEMBL8696169 | 0.81 | ALDH1A1 (0.48) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8692495 | 0.81 | RAB9A (0.54) | MAPTALDH1A1MEN1KMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849779-A | Pyrazole derivatives and their pharmaceutical use | JAPAN ENERGY CORPORATION (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0810217-A1 | Pyrazole derivatives and their pharmaceutical use as smooth muscle cell growth inhibitors | JAPAN ENERGY CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |